Friday, August 19, 2011

“The China Study” Chapter Two: A House of Proteins

I am going to use the same outline that I did for chapter one but this time I will add a brief vocabulary section since that is more prevalent in this chapter:
Salient points:
·         Carl Voit (1831-1908) determined that man needed 48.5g of protein per day yet recommended 118g because of a cultural bias at the time.
·         In early 1900’s USDA (whose head studied under Voit) recommended 125g of protein per day which later dropped to 55g.
·         Protein is composed of chains of amino acids which are broken down to replace those that wear out naturally.
·         “…through enormously complex metabolic systems, the human body can derive all the essential amino acids from the natural variety of plant protein that we encounter every day.
·         Peanuts are a good source of protein but can be contaminated with aflatoxin (a potent carcinogen).  Peanut butter is more likely to be contaminated than whole peanuts.
·         The foods most likely to be contaminated with aflatoxin are peanuts and corn.
·         In the Philippines the children most likely to have live cancer were those eating a diet high in animal protein (i.e. most similar to the US diet).
·         A research paper out of India also showed that lab rats exposed to aflatoxin when fed a diet of 20% protein all got liver cancer, 100%.  Rats fed a 5% protein diet did not get liver cancer, not one.
·         A problem with nutritional science is that you aren’t going to get absolute proof there are too many confounding factors.  However you can determine what is likely to be true using statistics.
Vocabulary:
Observational studies – means to simply record what is done and then record the outcome (the obvious example is the China Study or the Nurses’ Health Study)
Interventional studies – to intentionally intervene and measure the outcome (common examples of this would be clinical trials for medications)
Positively correlated – when one item increases so does the other (example increasing alcohol intake increases breast cancer incidence)
Inversely correlated – one item goes up and the other goes down (example as higher fiber diets are associated with a reduction in colon cancer)
Statistical significance – is attempting to measure whether the result is reliable/reproducible or due to chance, typically given as 95% confidence interval.
Mechanism of action – this simply means there is an underlying process that can explain why the particular outcome makes sense
Metanalysis – is the statistical grouping of many different studies that are then analyzes as a one data set
Observations:
I am definitely the sort of person that responds to scientific information. Knowing that Dr. Campbell was motivated by a desire to follow the evidence no matter where it took him was comforting to me.  I think it is very easy to develop a personal bias and miss things if any of us aren’t careful.  There are a few other doctors (Fuhrman, Barnard and Esselstyn) that I also believe followed the evidence which led them to become advocates for the vegan diet.  Whenever I am reading health information I always consider the source. For example I would do a lot more research to confirm something that was posted on PETA’s website than I would if I read it on Dr. Fuhrman’s.  Since Dr. Campbell’s career was built on research and his conclusions bucked the system personally I find him more credible.
It was extremely disturbing to me that protein requirements were based more on societal norms/expectations than science.  However we still see the same thing happening today.  I know many health conscious people who believe that they need to consume more protein to build muscle. Many people have been surprised to find that I am vegan because I am not a waif which is what most people expect vegans to be apparently.   In fact I had one person actually comment that “I looked healthy unlike most vegans" what that meant.  Needless to say I wasn’t sure how to take that be decided to consider it a compliment and keep going.  ;-)
When I took the Cornell program the “ah ha” moment for me was learning that breast milk was approximately 6% protein. Think about that for a minute. At a time in life where we are growing as rapidly as any other time we are designed to eat a diet that is 6% protein.  How can it be logical to eat a diet that is 20-30% protein when we are no longer growing?  It doesn’t make any sense and yet most people consume far more than 6% of their calories from protein.
Now I want to know what did you found interesting in this chapter?   I need to run out to take care of my Friday errands soon and stop by my parents.  But I can’t wait to read your comments when I get home.  Talk with you soon I hope.  :-)

12 comments:

  1. First off: After reading the first few chapters of this book, I was terrified to eat peanuts! The discussion of aflatoxin and cancer was too disturbing to ignore. Peanuts and peanut butter are now on my "only buy organic" list. Not a guarantee, but a better chance of reducing aflatoxin exposure.

    Campbell's discussion of protein illustrated how that nutrient has achieved an "elevated status" in our diet. All worship at the shrine of PROTEIN! When I ate a vegan diet, the first $@#!! question out of *everyone's* mouth was "where do you get your protein?". With that response, it's pretty clear how little most know about what they eat. Personally, I think the Meat Lobby has a great deal to do with mis-information about protein requirements.

    Another thing I'd like to discuss is that Campbell himself at the end of this chapter states that "correlation does not equal causation"; rather that an examination of all studies must be considered as a "Meta-analysis". I think it's important to mention this because most people who dispute the conclusions in China Study use "correlation does not equal causation" as their primary argument. Even Campbell acknowledges this...the whole is greater than the sum of the parts...the broader picture must be examined.

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  2. Kit,

    I believe the peanut butter with aflatoxin that was tested was what was available in the Phillipines given the context in which is was discussed. However I do only buy organic peanut butter. In fact 95% of what I buy is organic or eco-farmed. If you are concerned you can but your own peanuts, since mold is obvious, and make your own peanut butter. It is very easy to do in the food processor though it does take a long time if you are also shelling the peanuts which is what I did.

    I came to the conclusion that the vast majority of people don't know much about nutrition and most of what they think they know is flat out wrong. It is scary! I blame the education system for much of this misinformation.

    The people whom you mention that are arguing that correlation does not equal causation are doing so because they have no desire to change their diet. When I first began studying nutrition I was shocked that none of my friends were interested in making the switch and they used a variety of reasons. I will point out that these are the same people who seem to feel animal protein is required though they have no proof of that either. I think it comes down to people are open to change or they aren't Personally I spend very little time now trying to "convince" anyone of the science. Either they are open to it or they aren't. Does that make any sense?

    Ali

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  3. >>"Personally I spend very little time now trying to "convince" anyone of the science. Either they are open to it or they aren't."

    Yes, I agree. It's hard not to try to educate/convince loved ones when we know how significantly their health could improve. But sometimes it's like beating your head against a wall. Sigh.

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  4. Bummer. I'm just not going to be able to finish this chapter before going out of town, but I'll look forward to catching up to you folks late next week!

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  5. This chapter was a bit dry, but necessary. It's so easy for "research" to be skewed. It's nice to have some information about what to look for. Secondly, I think you always have to look at the funding source for the research.

    Just a bit about proteins and me...
    I'm on dialysis and have been since December. I do peritoneal dialysis which causes me to lose protein on top of what I'm losing already through my urine. I didn't tell my nurse about my "diet" because I knew I would get flack. The nutritionist freaked out a little at my last appointment when I shared that with her. She begged me to at least eat eggs and fish (which I still do about once a week). Once a month, my blood is drawn for labs. My iron reserves were UP (thank you green leafy veggies), and so was my hemoglobin, the highest it has been since starting dialysis. At one point I was taking Epogen injections to stimulate the bone marrow to produce red blood cells because I was so anemic. So this is a BIG DEAL. The nutritionist does not want me eating beans, nuts, seeds, or whole grains because of the high phosphorus count. I did anyway. My phosphorus was lower than last month. The all-important protein did go down, but only by a fractional amount. The doctor was still very happy with that number.
    It's amazing to me that I had to argue with the nutritionist about this. The doctor and the nurse I could see...but the nutritionist? That makes me wonder: Is standard education for nutrition much like standard education for doctors? They look at the details and not the big picture???

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  6. I was trying to read some opinions/studies that question the results of Campbell's rat studies, but 1)got confused and 2)had to leave town because my FIL is in the hospital. There was something about a protective effect of milk protein that wasn't published...it was very confusing to me. Ali, have you read any of those critical reviews and do you put any weight on them?

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  7. Brandy,

    Yes, this book can be a bit dry, but science tends to be like that. ;-) I will try to make my comments a bit more interesting to compensate.

    I always look at the funding source too it isn't just you. Additionally I like to know if the studies are double-blinded and placebo controlled.

    Great question about nutrition education. I know a number of registered dieticians and only one who is vegan and I met her through the blog. Sadly I can name a number of RDs who eat a diet I don't consider healthy. Dietitians are like everyone else they have their own built in biases that seems to cloud their judgement. It shouldn't be like that but it is. Also like you said they look at the details and tend to miss the big picture.

    I am happy to hear about your lab results. With weekly blood tests you can see the changes much more quickly so that you can react. I hope the good news continues. :-)

    Ali

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  8. Laura,

    Sorry to hear about your FIL I hope he makes a quick recovery.

    When you get a chance please post the URL for the items you are reading so we can all read and discuss them in detail. You could also send me the link in an email and I will post them for you. I have read many of these articles bashing the results of the China Study and none of them held up scientifically for me.

    There is science to suggest that the whey portion of milk protein is beneficial but that is very misleading. The protein composition of milk is 87% casein and 13% whey. The vast majority of the protein is casein which is the problem. I would say consuming milk is like drinking arsenic (casein) and a little antidote (whey) and hoping the antidote is stronger than the poison. Does that make sense? Is the whey protein what you were asking about?

    Ali

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  9. Oh no! I posted a LONG response this morning, and it seems to have disappeared! Very discouraged . . .

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  10. Here's a quick-and-dirty list of the sites I linked in my response. :-(

    http://www.cholesterol-and-health.com/China-Study.html

    http://www.ansci.cornell.edu/plants/toxicagents/aflatoxin/aflatoxin.html

    http://www.niehs.nih.gov/health/impacts/aflatoxin/index.cfm

    http://www.ehso.com/ehshome/aflatoxin.php

    http://scienceblogs.com/moleculeoftheday/2008/02/aflatoxin_you_got_mycotoxin_in.php

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  11. Cindy,

    I wonder how your comment disappeared. When I get home from Richmond I will see if I can restore it.

    Ali

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  12. Brandy, I didn't know if you were aware of Jack Norris, but he posted something to his blog Tuesday asking for connections to vegans on dialysis! Here's the link . . .

    http://jacknorrisrd.com/?p=2110

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